D'Onofrio was born on June 30, 1959, in Brooklyn. He is of Italian descent, with ancestors from Naples. His parents Gennaro and Phyllis D'Onofrio met while Gennaro was stationed in Hawaii with the U.S. Air Fo… See more

After graduating from high school, D'Onofrio started to appear on stage. During an 18-month stint at the University of Colorado in Boulder, he was involved with small, community-theater productions. He later studied … See more

In the early 1990s, D'Onofrio dated actress Greta Scacchi, with whom he starred in several films during that period (including The Player and Fires Within). Their daughter is actress Leila George (b. March 20, 1992).
On March … See more